Sometimes bold and italics are called for; for example, when convention asks us to bold a key term (as in the lead of an encyclopedia article), but that key term is the title of a work that should be italicized, or a Latin binomial taxon.
Sometimes bold and italics are called for; for example, when convention asks us to bold a key term (as in the lead of an encyclopedia article), but that key term is the title of a work that should be italicized, or a Latin binomial taxon.