Thread:Project:Support desk/Database "ENGINE=MyISAM, DEFAULT CHARSET=binary" help/reply

Yes, binary is what is recommended. The other option would be UTF-8, but if you do not have a charset problem currently, I would just not touch this setting. See Manual:$wgDBTableOptions for more information! Btw: This value is used for new tables/columns, changing it won't change what you already have in the DB.